Article
Association of heterozygous CCR5Δ32 deletion with survival in HIV-infection: A cohort study.
Antiviral research - 1 Feb 2018
Ruiz-Mateos Ezequiel, Tarancon-Diez Laura, Alvarez-Rios Ana I, Dominguez-Molina Beatriz, Genebat Miguel, Pulido Ildefonso, Abad Maria Antonia, Muñoz-Fernandez Maria Angeles, Leal Manuel
Abstract excerpt
The role of a 32 base pair deletion in the CCR5 gene (CCR5Δ32) in HIV-disease progression and response to combined antiretroviral therapy (cART) is well established. However, the impact of CCR5Δ32 in the long-term survival pre-cART and after cART introduction in a large cohort of HIV-infected patients is unknown. We analyzed the association of CCR5Δ32 deletion in the long-term survival of HIV-infected patients...
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