Article
Frequency of a mutated CCR-5 allele (delta32) among Italian healthy donors and individuals at risk of parenteral HIV infection.
AIDS research and human retroviruses - 1 Mar 1999
Zamarchi R, Indraccolo S, Minuzzo S, Coppola V, Gringeri A, Santagostino E, Vicenzi E, De Silvestro G, Biagiotti R, Baldassarre C, Chieco-Bianchi L, Amadori A
Abstract excerpt
The aim of this study was to assess the frequency of a truncated allele of the CCR-5 gene (delta32) in Italy, and address its possible role in parenteral HIV transmission, as well as its influence in HIV-associated disease progression. In 371 unrelated seronegative healthy blood donors the delta32 allele frequency was 0.047; this figure was significantly different from those reported in northern America and...
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