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Article

Could the CCR5-Delta32 mutation be protective in SARS-CoV-2 infection?

Physiological research - 16 Dec 2021

Starcevic Cizmarevic N, Kapovic M, Roncevic D, Ristic S

Abstract excerpt

Increasing evidence points to host genetics as a factor in COVID-19 prevalence and outcome. CCR5 is a receptor for proinflammatory chemokines that are involved in host responses, especially to viruses. The CCR5-delta32 minor allele is an interesting variant, given the role of CCR5 in some viral infections, particularly HIV-1. Recent studies of the impact of CCR5-delta32 on COVID-19 risk and severity have yielded...

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Identifiers

PMID: 34913355
DOI: 10.33549/physiolres.934725
PMCID: PMC8884372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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