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Article

The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm.

Molecular and cellular biology - 1 Dec 2004

Shima Naoko, Munroe Robert J, Schimenti John C

Abstract excerpt

chaos1 (for chromosome aberrations occurring spontaneously 1) is a recessive mutation that was originally identified in a phenotype-based screen for chromosome instability mutants in mice. Mutant animals exhibit significantly higher frequencies of spontaneous and radiation- or mitomycin C-induced micronucleated erythrocytes, indicating a potential defect in homologous recombination or interstrand cross-link...

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Share to Ataxia Telangiectasia Mutated Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15542845
DOI: 10.1128/MCB.24.23.10381-10389.2004
PMCID: PMC529050

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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