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Article

A novel protein, MAPO1, that functions in apoptosis triggered by O6-methylguanine mispair in DNA.

Oncogene - 26 Feb 2009

Komori K, Takagi Y, Sanada M, Lim T-H, Nakatsu Y, Tsuzuki T, Sekiguchi M, Hidaka M

Abstract excerpt

O(6)-Methylguanine produced in DNA induces mutation due to its ambiguous base-pairing properties during DNA replication. To suppress such an outcome, organisms possess a mechanism to eliminate cells carrying O(6)-methylguanine by inducing apoptosis that requires the function of mismatch repair pr...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19137017
DOI: 10.1038/onc.2008.462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19137017-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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