Article
[Gene p53 mutation and prognosis in bladder tumors].
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica - 1 Feb 1997
Polito M, Minardi D, Giannulis I, Montironi R, Yehia M, Cristalli A F, Muzzonigro G
Abstract excerpt
The choice of treatment for bladder tumors is based on pathological criteria, i.e. staging and grading mainly. It has recently been observed that genetic alterations that involve activation of oncogenes and inactivation of suppressor genes can occur during tumorigenesis. p53 protein is coded for by a genes on chromosome 17, and is able to suppress malignant transformation and proliferation; it can be important in...
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