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Article

Focal adhesion kinase is not required for integrin function or viability in Drosophila.

Development (Cambridge, England) - 1 Dec 2004

Grabbe Caroline, Zervas Christos G, Hunter Tony, Brown Nicholas H, Palmer Ruth H

Abstract excerpt

The mammalian focal adhesion kinase (FAK) family of non-receptor protein-tyrosine kinases has been implicated in controlling a multitude of cellular responses to the engagement of cell-surface integrins and G-protein-coupled receptors. The high level of sequence conservation between the mammalian proteins and the Drosophila homologue of FAK, Fak56, suggested that it would have similar functions. However, we show...

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Identifiers

PMID: 15525665
DOI: 10.1242/dev.01462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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