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Article

Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth.

Neural development - 16 Oct 2008

Tsai Pei-I, Kao Hsiu-Hua, Grabbe Caroline, Lee Yu-Tao, Ghose Aurnab, Lai Tzu-Ting, Peng Kuan-Po, Van Vactor David, Palmer Ruth H, Chen Ruey-Hwa, Yeh Shih-Rung, Chien Cheng-Ting

Abstract excerpt

BACKGROUND: Focal adhesion kinase (FAK) functions in cell migration and signaling through activation of the mitogen-activated protein kinase (MAPK) signaling cascade. Neuronal function of FAK has been suggested to control axonal branching; however, the underlying mechanism in this process is not clear. RESULTS: We have generated mutants for the Drosophila FAK gene, Fak56. Null Fak56 mutants display overgrowth of...

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Identifiers

PMID: 18925939
DOI: 10.1186/1749-8104-3-26
PMCID: PMC2576229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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