Article
[Association of the structure of the glucocorticoid receptor and single nucleotide NR3C1 gene polymorphisms with metabolic disorders].
Problemy endokrinologii - 25 Feb 2023
Brovkina S S, Dzherieva I S, Volkova N I, Shkurat T P, Goncharova Z A, Mashkina E V, Reshetnikov I B
Abstract excerpt
Glucocorticoid therapy is widely used in the treatment of various pathologies. Sensitivity to glucocorticoids (GC) has a serious impact not only on the effectiveness of their action, but also on the severity of side effects, the formation of risk factors and the development of cardiovascular diseases (CVD). Variability of sensitivity to GC causes different phenotypes and severity of metabolic disorders...
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