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Article

Confirmation of a major QTL influencing oral morphine intake in C57 and DBA mice using reciprocal congenic strains.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Apr 2005

Ferraro Thomas N, Golden Gregory T, Smith George G, Martin James F, Schwebel Candice L, Doyle Glenn A, Buono Russell J, Berrettini Wade H

Abstract excerpt

C57BL/6 (B6) and DBA/2 (D2) mice exhibit disparate behavior when tested for voluntary morphine intake in a two-bottle choice drinking paradigm with B6 mice consuming 10 times more drug than D2 mice. Previous genetic mapping studies identified a locus, Mop2, on the proximal part of chromosome 10 that explained over half of the genetic variance in this mouse model of opioid self-administration. We constructed a set...

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PMID: 15508023
DOI: 10.1038/sj.npp.1300592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Confirmation of a major QTL influencing oral morphine intake in C57 and DBA mice using reciprocal congenic strains.PMID 15508023Read ↗

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