Article
Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.
Neurochemical research - 1 Jul 2007
Vadasz Csaba, Saito Mariko, Gyetvai Beatrix M, Oros Melinda, Szakall Istvan, Kovacs Krisztina M, Prasad Vidudala V T S, Morahan Grant, Toth Reka
Abstract excerpt
One strategy to identify neurochemical pathways of addiction is to map the relevant genes. In the present study we used 43 B6.C and 35 B6.I inbred RQI mouse strains, carrying <3% donor genome on C57BL/6ByJ background, for gene mapping. The strains were phenotyped for consumption of alcohol (12% v/v) in a two-bottle-choice paradigm, and genotyped for 396 microsatellite markers. The current mapping study extends...
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