Article
Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains.
Nature genetics - 1 May 1994
Berrettini W H, Ferraro T N, Alexander R C, Buchberg A M, Vogel W H
Abstract excerpt
Quantitative trait loci mapping was used to identify the chromosomal location of genes which contribute to oral morphine preference (in a two-bottle choice paradigm) of C57BL/6J mice, compared to DBA/2J mice. An F2 intercross of these two strains (606 mice) was phenotyped for morphine preference and those mice demonstrating extreme values for morphine consumption (the highest and lowest 7.7%) were genotyped for...
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