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Article

The nuclear pore complex protein Elys is required for genome stability in mouse intestinal epithelial progenitor cells.

Gastroenterology - 1 May 2011

Gao Nan, Davuluri Gangarao, Gong Weilong, Seiler Christoph, Lorent Kristin, Furth Emma E, Kaestner Klaus H, Pack Michael

Abstract excerpt

BACKGROUND & AIMS: Elys is a conserved protein that directs nuclear pore complex (NPC) assembly in mammalian cell lines and developing worms and zebrafish. Related studies in these systems indicate a role for Elys in DNA replication and repair. Intestinal epithelial progenitors of zebrafish elys mutants undergo apoptosis early in development. However, it is not known whether loss of Elys has a similar effect in...

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Identifiers

PMID: 21315719
DOI: 10.1053/j.gastro.2011.01.048
PMCID: PMC3282118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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