Article
Targeted disruption of int-2 (fgf-3) causes developmental defects in the tail and inner ear.
Molecular reproduction and development - 1 Sept 1994
Mansour S L
Abstract excerpt
The int-2 gene (also designated fgf-3) was originally identified because its transcription is activated by the nearby integration of mouse mammary tumor virus in virus-induced tumors. Molecular analyses have revealed that the int-2 gene produces at least four mRNAs, all of which encode a protein that has 40-50% amino acid sequence similarity with the fibroblast growth factors (FGFs). Int-2 gene expression is...
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