Targeted disruption of int-2 (fgf-3) causes developmental defects in the tail and inner ear.

doi:10.1002/mrd.1080390111

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Article

Targeted disruption of int-2 (fgf-3) causes developmental defects in the tail and inner ear.

Molecular reproduction and development - 1 Sept 1994

Mansour S L

Abstract excerpt

The int-2 gene (also designated fgf-3) was originally identified because its transcription is activated by the nearby integration of mouse mammary tumor virus in virus-induced tumors. Molecular analyses have revealed that the int-2 gene produces at least four mRNAs, all of which encode a protein...

Topics

Alleles
Alternative Splicing
Animals
Ear, Inner
Embryonic and Fetal Development
Fibroblast Growth Factor 3
Fibroblast Growth Factors
Homozygote
Mice
Mice, Mutant Strains
Phenotype
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
RNA, Messenger
Tail

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