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Article

Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells.

Proceedings of the National Academy of Sciences of the United States of America - 2 May 2006

Pritsker Moshe, Ford Nicole R, Jenq Harry T, Lemischka Ihor R

Abstract excerpt

Embryonic stem (ES) cells hold great promise for the future of medicine. To elucidate the molecular mechanisms that control ES cell self-renewal and differentiation, a comprehensive knowledge of the molecules involved in these processes is required. Here we describe an effective approach for genomewide identification of functionally active genes in ES cells. This approach combines genetic screens based on cDNA...

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Identifiers

PMID: 16621925
DOI: 10.1073/pnas.0509861103
PMCID: PMC1458999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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