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Article

Analysis of K-RAS and P53 mutations in sputum samples.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005

Gao Weimin, Keohavong Phouthone

Abstract excerpt

Mutations in the P53 tumor suppressor gene and the K-RAS oncogene have frequently been found in sputum and bronchoalveolar lavage (BAL) samples of lung cancer patients, and also in samples from patients prior to presenting clinical symptoms of lung cancer, suggesting they may provide useful biomarkers for early lung cancer diagnosis. However, the detection of these mutations has been complicated by the fact that...

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PMID: 15502226
DOI: 10.1385/1-59259-840-4:217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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