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Article

p53 and ras gene mutations in lung cancer: implications for smoking and occupational exposures.

Journal of occupational and environmental medicine - 1 Jan 1995

Husgafvel-Pursiainen K, Ridanpää M, Anttila S, Vainio H

Abstract excerpt

This paper reviews mutational activation of ras oncogenes and inactivation of the p53 tumor suppressor gene in human lung cancer. We discuss the frequency, type, and location of mutations in these genes in relation to known etiological factors for lung cancer. The most studied examples of these are exposure to tobacco smoke, and to radon and asbestos fibers at work. We summarize data from our laboratory on K-ras...

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Identifiers

PMID: 7620945
DOI: 10.1097/00043764-199501000-00010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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