Article
[Detection of oncogenic mutations in sputum and its diagnostic value of lung cancer].
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases - 1 Apr 1998
Wang L, Wang G, Xia X
Abstract excerpt
OBJECTIVE: To find a new method to molecular biological detection of lung cancer. METHOD: The sputum specimens from 96 cases of lung cancer and other lung patients were detected for K-ras and p53 mutations by using polymerase chain reaction(PCR) and restriction fragment length polymorphism and and immunohistochemistry (IHC) techniques. RESULT: 38 out of 62 sputum specimens of lung cancer patients were positive...
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