Article
Molecular genetic tumor markers in the early diagnosis and screening of non-small-cell lung cancer.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jan 1995
Jacobson D R, Fishman C L, Mills N E
Abstract excerpt
BACKGROUND: Little progress has been made in decreasing lung cancer mortality by applying conventional methods to early diagnosis and screening. Recent advances in molecular oncology, however, have provided tools which may be of use in this area. Many genes involved in controlling cell growth and differentiation are abnormal in lung cancer cells. Such genes include K-ras, p53, rb, myc, her2/neu, and probably one...
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