K-ras mutation in sputum of patients with or without lung cancer.

Article

K-ras mutation in sputum of patients with or without lung cancer.

Journal of cellular biochemistry. Supplement - 1 Jan 1996

Ronai Z, Yabubovskaya M S, Zhang E, Belitsky G A

Abstract excerpt

K-ras mutation appears in about 60% of patients with non-small-cell lung cancer (NSCLC). This frequency and its presence in normal appearing tissues point to the potential of ras oncogene mutation to serve as a good biomarker. Using enriched PCR (EPCR), which enables the detection of one mutant a...

Topics

Adult
Aged
DNA Mutational Analysis
Genes, ras
Humans
Lung Diseases
Lung Neoplasms
Middle Aged
Mutation
Polymerase Chain Reaction
Sputum

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