Overview of genetic and molecular events in the pathogenesis of lung cancer.

doi:10.1378/chest.103.1_supplement.1s

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Article

Overview of genetic and molecular events in the pathogenesis of lung cancer.

Chest - 1 Jan 1993

Johnson B E, Kelley M J

Abstract excerpt

Research on dominant oncogenes and tumor suppressor genes has characterized differences in genetic lesions between small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) and identified associations with clinical parameters. More than one half of all lung cancers contain a mutation o...

Topics

Carcinoma, Non-Small-Cell Lung
Carcinoma, Small Cell
Genes, p53
Genes, ras
Humans
Lung Neoplasms
Mutation
Smoking
Tumor Cells, Cultured

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