Article
Overview of genetic and molecular events in the pathogenesis of lung cancer.
Chest - 1 Jan 1993
Johnson B E, Kelley M J
Abstract excerpt
Research on dominant oncogenes and tumor suppressor genes has characterized differences in genetic lesions between small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) and identified associations with clinical parameters. More than one half of all lung cancers contain a mutation of the p53 tumor suppressor gene. There does not appear to be an association between the presence of this mutation and...
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