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Article

Polymorphisms in the P-selectin (CD62P) and P-selectin glycoprotein ligand-1 (PSGL-1) genes and coronary heart disease.

Clinical chemistry and laboratory medicine - 1 Jan 2004

Bugert Peter, Vosberg Marion, Entelmann Mathias, Jahn Jürgen, Katus Hugo A, Klüter Harald

Abstract excerpt

P-selectin and its ligand, PSGL-1, are cell adhesion molecules that facilitate interaction of platelets, leukocytes and endothelial cells. Polymorphisms of these genes have been reported to be associated with coronary heart disease (CHD). In the present study, we characterized the entire coding regions of P-selectin and PSGL-1 genes in CHD patients and healthy controls. The 17 exons of the P-selectin gene and...

Topics

Adult
Aged
Case-Control Studies
Coronary Artery Disease
Female
Genotype
Humans
Ligands
Male
Membrane Glycoproteins
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mucins

P-Selectin

Polymerase Chain Reaction

Polymorphism, Single Nucleotide

Recombinant Proteins

Source

Identifiers

PMID: 15497463
DOI: 10.1515/CCLM.2004.202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15497463-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Polymorphisms in the P-selectin (CD62P) and P-selectin glycoprotein ligand-1 (PSGL-1) genes and coronary heart disease.PMID 15497463Read ↗

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