Article
Contribution of SELP and PSGL-1 genotypes and haplotypes to the presence of coronary heart disease in Tunisians.
Molecular biology reports - 1 Jan 2011
Ghazouani Lakhdar, Abboud Nesrine, Khalifa Sonia Ben Hadj, Perret Claire, Nicaud Viviane, Almawi Wassim Youssef, Cambien François, Mahjoub Touhami
Abstract excerpt
P-selectin (SELP) and its counter-receptor, P-selectin glycoprotein ligand-1 (PSGL-1), play key role in the transient attachment of leukocytes to endothelial cells predisposing to coronary heart disease (CHD). In the current report, 293 angiographically proven CHD patients and 327 age, gender, and race-matched controls were included. Our aim was to evaluate the contribution to CHD of the following SNPs: C-2123G,...
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