Article
Association between P-selectin gene polymorphisms and soluble P-selectin levels and their relation to coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2001
Barbaux S C, Blankenberg S, Rupprecht H J, Francomme C, Bickel C, Hafner G, Nicaud V, Meyer J, Cambien F, Tiret L
Abstract excerpt
P-selectin is a cellular adhesion molecule that mediates the interaction of activated endothelial cells or platelets with leukocytes. Increased levels of soluble P-selectin have been reported in various cardiovascular disorders. We measured serum soluble P-selectin levels as well as 3 polymorphisms of the P-selectin gene (C-2123G, A-1969G, and Thr715Pro) in a large cohort of patients with documented coronary...
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