Article
Association between P-selectin gene polymorphisms and soluble P-selectin levels and their relation to coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2001
Barbaux S C, Blankenberg S, Rupprecht H J, Francomme C, Bickel C, Hafner G, Nicaud V, Meyer J, Cambien F, Tiret L
Abstract excerpt
P-selectin is a cellular adhesion molecule that mediates the interaction of activated endothelial cells or platelets with leukocytes. Increased levels of soluble P-selectin have been reported in various cardiovascular disorders. We measured serum soluble P-selectin levels as well as 3 polymorphis...
Topics
- Cohort Studies
- Coronary Artery Disease
- Female
- Humans
- Male
- Middle Aged
- P-Selectin
- Polymorphism, Single Nucleotide
- Risk Factors
- Smoking