Article
The variable number of tandem repeat polymorphism in the P-selectin glycoprotein ligand-1 gene is not associated with coronary heart disease.
Journal of molecular medicine (Berlin, Germany) - 1 Aug 2003
Bugert Peter, Hoffmann Michael M, Winkelmann Bernhard R, Vosberg Marion, Jahn Jürgen, Entelmann Matthias, Katus Hugo A, März Winfried, Mansmann Ulrich, Boehm Bernhard O, Goerg Siegfried, Klüter Harald
Abstract excerpt
Genes involved in inflammatory processes are candidates for predisposition to prothrombotic syndromes. The variable number of tandem repeat (VNTR) polymorphism in the P-selectin glycoprotein ligand (PSGL)-1 gene has been associated with ischemic cerebrovascular disease but not with coronary heart disease (CHD). We assessed the effect of the VNTR polymorphism on CHD in two independent case/control studies. In the...
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