Article
Impact of variables of the P-selectin - P-selectin glycoprotein ligand-1 axis on leukocyte-platelet interactions in cardiovascular disease.
Thrombosis and haemostasis - 1 Apr 2015
Gremmel Thomas, Koppensteiner Renate, Kaider Alexandra, Eichelberger Beate, Mannhalter Christine, Panzer Simon
Abstract excerpt
The formation of leukocyte-platelet aggregates (LPA), through the P-selectin - P-selectin glycoprotein ligand (PSGL)-1 axis, plays a pivotal role in atherothrombosis. In order to investigate the influence of platelet (pP-selectin) and soluble P-selectin (sP-selectin), and of variations in the gen...
Topics
- Adult
- Aged
- Aged, 80 and over
- Angioplasty
- Blood Platelets
- Cardiovascular Diseases
- Case-Control Studies
- Enzyme-Linked Immunosorbent Assay
- Female
- Flow Cytometry
- Gene Frequency
- Genetic Predisposition to Disease
- Genetic Variation
- Humans
- Male
- Membrane Glycoproteins
- Middle Aged
- Monocytes