Soluble P-selectin levels, P-selectin polymorphisms and cardiovascular disease.

doi:10.1046/j.1538-7836.2003.00312.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Soluble P-selectin levels, P-selectin polymorphisms and cardiovascular disease.

Journal of thrombosis and haemostasis : JTH - 1 Aug 2003

Carter A M, Anagnostopoulou K, Mansfield M W, Grant P J

Abstract excerpt

P-selectin is a member of the selectin family of cell adhesion molecules which are important in the transient attachment of leukocytes to endothelial cells and platelets. A number of polymorphisms in the gene encoding P-selectin have been identified. Objectives were to investigate the relationship of soluble P (sP)-selectin with P-selectin gene polymorphisms and coronary artery disease (CAD). Two hundred and...

Topics

Aged
Alleles
Cardiovascular Diseases
Case-Control Studies
Cell Adhesion
Coronary Angiography
Coronary Artery Disease
E-Selectin
Female
Genotype
Humans
Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Myocardial Infarction

P-Selectin

Polymorphism, Genetic

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 12911583
DOI: 10.1046/j.1538-7836.2003.00312.x

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12911583-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Soluble P-selectin levels, P-selectin polymorphisms and cardiovascular disease.PMID 12911583Read ↗

Association between P-selectin gene polymorphisms and soluble P-selectin levels and their relation to coronary artery disease.Semantic proximity Read ↗

The P-selectin gene is highly polymorphic: reduced frequency of the Pro715 allele carriers in patients with myocardial infarction.Semantic proximity Read ↗

High concentrations of soluble P-selectin are associated with risk of venous thromboembolism and the P-selectin Thr715 variant.Semantic proximity Read ↗

Clinical and genetic correlates of soluble P-selectin in the community.Semantic proximity Read ↗

The Ser290Asn and Thr715Pro Polymorphisms of the SELP Gene Are Associated with A Lower Risk of Developing Acute Coronary Syndrome and Low Soluble P-Selectin Levels in A Mexican Population ‡.Semantic proximity Read ↗

P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: the Atherosclerosis Risk in Communities Study.Semantic proximity Read ↗

Association of SELP Polymorphisms with Soluble P-Selectin Levels and Vascular Risk in Patients with Type 2 Diabetes Mellitus: A Case-Control Study.Semantic proximity Read ↗

The P-selectin gene Pro715 allele and low levels of soluble P-selectin are associated with reduced P2Y12 adenosine diphosphate receptor reactivity in clopidogrel-treated patients.Semantic proximity Read ↗

Soluble P-selectin, SELP polymorphisms, and atherosclerotic risk in European-American and African-African young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study.Semantic proximity Read ↗

Impact of variables of the P-selectin - P-selectin glycoprotein ligand-1 axis on leukocyte-platelet interactions in cardiovascular disease.Semantic proximity Read ↗

Effects of toll-like receptor-4 gene polymorphisms on soluble P-selectin and von Willebrand factor levels in hypercholesterolemic patients.Semantic proximity Read ↗

Polymorphisms in the P-selectin (CD62P) and P-selectin glycoprotein ligand-1 (PSGL-1) genes and coronary heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.