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Article

Detection of a large deletion in the P-selectin (SELP) gene.

Molecular and cellular probes - 1 Jun 2010

Pasquali Alessandra, Trabetti Elisabetta, Romanelli Maria Grazia, Galavotti Roberta, Martinelli Nicola, Girelli Domenico, Gambaro Giovanni, Olivieri Oliviero, Pignatti Pier Franco

Abstract excerpt

P-selectin is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. In this study of 51 polymorphisms in candidate genes for cardiovascular disease in 1561 individuals, we identified a new allelic variant of the SELP gene, g.18196_20704del, that determined the lack of genotyping for one polymorphism in one individual. It is a deletion of 2509 nucleotides which starts in...

Topics

Base Sequence
Coronary Artery Disease
Gene Deletion
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Molecular Sequence Data
P-Selectin
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Source

Identifiers

PMID: 19948214
DOI: 10.1016/j.mcp.2009.11.006

Genes

SELP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19948214-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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