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Article

P-selectin gene polymorphisms and risk of coronary heart disease among Tunisians.

Journal of thrombosis and thrombolysis - 1 Oct 2009

Ghazouani Lakhdar, Abboud Nesrine, Khlifa Sonia Bel-Hadj, Perret Claire, Nicaud Viviane, Cambien François, Almawi Wassim Y, Mahjoub Touhami

Abstract excerpt

P-selectin plays a key role in inflammation and atherosclerosis, and polymorphic variants of P-selectin were implicated in the pathogenesis of atherosclerotic and inflammatory changes, including coronary heart disease (CHD) in many ethnic groups. We investigated the contribution of P-selectin promoter (-2123C/G, -1969G/A) and exon (Ser290Asn, Asn562Asp, Thr715Pro) polymorphisms to CHD genetic susceptibility among...

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PMID: 19082691
DOI: 10.1007/s11239-008-0297-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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