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Article

A torrid zone on mouse chromosome 1 containing a cluster of recombinational hotspots.

Genetics - 1 Feb 2005

Kelmenson Peter M, Petkov Petko, Wang Xiaosong, Higgins David C, Paigen Beverly J, Paigen Kenneth

Abstract excerpt

Within the 2.38-Mb Ath1 region of mouse chromosome 1, 42 of 45 genetic crossovers from crosses between C57BL/6J (B6) and either C3H/HeJ (H) or Mus spretus (SPRET) occurred in four zones (A-D); zone A, 100 kb long, contained a cluster of at least four recombination hotspots. F1 sperm assays indicate that within this "torrid zone" the most active hotspot (A3) can initiate recombination on H and SPRET but not B6...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred C3H

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Share to Repetitive Sequences, Nucleic Acid

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Source

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Identifiers

PMID: 15489519
DOI: 10.1534/genetics.104.035063
PMCID: PMC1449111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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