Article
Multiple loci contribute to genome-wide recombination levels in male mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2010
Murdoch Brenda, Owen Nichole, Shirley Sofia, Crumb Sara, Broman Karl W, Hassold Terry
Abstract excerpt
Recent linkage-based studies in humans suggest the presence of loci that affect either genome-wide recombination rates, utilization of recombination hotspots, or both. We have been interested in utilizing cytological methodology to directly assess recombination in mammalian meiocytes and to identify recombination-associated loci. In the present report we summarize studies in which we combined a cytological assay...
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