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Article

Structural Variation Shapes the Landscape of Recombination in Mouse.

Genetics - 1 Jun 2017

Morgan Andrew P, Gatti Daniel M, Najarian Maya L, Keane Thomas M, Galante Raymond J, Pack Allan I, Mott Richard, Churchill Gary A, de Villena Fernando Pardo-Manuel

Abstract excerpt

Meiotic recombination is an essential feature of sexual reproduction that ensures faithful segregation of chromosomes and redistributes genetic variants in populations. Multiparent populations such as the Diversity Outbred (DO) mouse stock accumulate large numbers of crossover (CO) events between founder haplotypes, and thus present a unique opportunity to study the role of genetic variation in shaping the...

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Source

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Identifiers

PMID: 28592499
DOI: 10.1534/genetics.116.197988
PMCID: PMC5499175

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Source receipt: pubmed, retrieved 7 Sept 2026.

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