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Article

Patterns of recombination activity on mouse chromosome 11 revealed by high resolution mapping.

PloS one - 8 Dec 2010

Billings Timothy, Sargent Evelyn E, Szatkiewicz Jin P, Leahy Nicole, Kwak Il-Youp, Bektassova Nazira, Walker Michael, Hassold Terry, Graber Joel H, Broman Karl W, Petkov Petko M

Abstract excerpt

The success of high resolution genetic mapping of disease predisposition and quantitative trait loci in humans and experimental animals depends on the positions of key crossover events around the gene of interest. In mammals, the majority of recombination occurs at highly delimited 1-2 kb long sites known as recombination hotspots, whose locations and activities are distributed unevenly along the chromosomes and...

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Identifiers

PMID: 21170346
DOI: 10.1371/journal.pone.0015340
PMCID: PMC2999565

Genes

CAST
PRDM9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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