Article
Prdm9 controls activation of mammalian recombination hotspots.
Science (New York, N.Y.) - 12 Feb 2010
Parvanov Emil D, Petkov Petko M, Paigen Kenneth
Abstract excerpt
Mammalian meiotic recombination, which preferentially occurs at specialized sites called hotspots, ensures the orderly segregation of meiotic chromosomes and creates genetic variation among offspring. A locus on mouse chromosome 17, which controls activation of recombination at multiple distant h...
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