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Article

Polymorphism in the activity of human crossover hotspots independent of local DNA sequence variation.

Human molecular genetics - 1 May 2006

Neumann Rita, Jeffreys Alec J

Abstract excerpt

Meiotic crossovers in the human genome cluster into highly localized hotspots identifiable indirectly from patterns of DNA diversity and directly by high-resolution sperm typing. Little is known about factors that control hotspot activity and the apparently rapid turnover of hotspots during recent evolution. Clues can, however, be gained by characterizing variation in sperm crossover activity between men....

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Identifiers

PMID: 16543360
DOI: 10.1093/hmg/ddl063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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