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Article

Genome-wide screen for genes with effects on distinct iron uptake activities in Saccharomyces cerevisiae.

Genetics - 1 Jan 2005

Lesuisse Emmanuel, Knight Simon A B, Courel Maïté, Santos Renata, Camadro Jean-Michel, Dancis Andrew

Abstract excerpt

We screened a collection of 4847 haploid knockout strains (EUROSCARF collection) of Saccharomyces cerevisiae for iron uptake from the siderophore ferrioxamine B (FOB). A large number of mutants showed altered uptake activities, and a few turned yellow when grown on agar plates with added FOB, indicating increased intracellular accumulation of undissociated siderophores. A subset consisting of 197 knockouts with...

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Identifiers

PMID: 15489514
DOI: 10.1534/genetics.104.035873
PMCID: PMC1448889

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Source receipt: pubmed, retrieved 7 Sept 2026.

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