Article
A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae.
BMC genomics - 15 Nov 2009
Arita Adriana, Zhou Xue, Ellen Thomas P, Liu Xin, Bai Jingxiang, Rooney John P, Kurtz Adrienne, Klein Catherine B, Dai Wei, Begley Thomas J, Costa Max
Abstract excerpt
BACKGROUND: The understanding of the biological function, regulation, and cellular interactions of the yeast genome and proteome, along with the high conservation in gene function found between yeast genes and their human homologues, has allowed for Saccharomyces cerevisiae to be used as a model organism to deduce biological processes in human cells. Here, we have completed a systematic screen of the entire set...
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