Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide analysis of iron-dependent growth reveals a novel yeast gene required for vacuolar acidification.

The Journal of biological chemistry - 6 Feb 2004

Davis-Kaplan Sandra R, Ward Diane McVey, Shiflett Shelly L, Kaplan Jerry

Abstract excerpt

We conducted a genome-wide screen in the budding yeast Saccharomyces cerevisiae of 4,792 homozygous diploid deletions to identify genes that function in iron metabolism. Strains unable to grow on iron-restricted medium contained deletions of genes that encode the structural components of the high affinity iron transport system (FET3, FTR1), the iron-sensing transcription factor AFT1 or genes required for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ceruloplasmin
Share to Copper
Share to Genome, Fungal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydrogen-Ion Concentration

Share to Open Reading Frames

Share to Vacuolar Proton-Translocating ATPases

Share to Vacuoles

Source

Identifiers

PMID: 14594803
DOI: 10.1074/jbc.M310680200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide analysis of iron-dependent growth reveals a novel yeast gene required for vacuolar acidification.PMID 14594803Read ↗

Genome-wide screen for genes with effects on distinct iron uptake activities in Saccharomyces cerevisiae.Semantic proximity Read ↗

Characterization of the yeast ionome: a genome-wide analysis of nutrient mineral and trace element homeostasis in Saccharomyces cerevisiae.Semantic proximity Read ↗

High-resolution genome-wide scan of genes, gene-networks and cellular systems impacting the yeast ionome.Semantic proximity Read ↗

A genomic screen for yeast vacuolar membrane ATPase mutants.Semantic proximity Read ↗

Saccharomyces cerevisiae mutants altered in vacuole function are defective in copper detoxification and iron-responsive gene transcription.Semantic proximity Read ↗

Functional Genomic Analysis of Fluconazole Susceptibility in the Pathogenic Yeast <i>Candida glabrata</i> : Roles of Calcium Signaling and MitochondriaSemantic proximity Read ↗

The long physiological reach of the yeast vacuolar H+-ATPase.Semantic proximity Read ↗

Genome-wide screen for oxalate-sensitive mutants of Saccharomyces cerevisiae.Semantic proximity Read ↗

A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system.Semantic proximity Read ↗

A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.Semantic proximity Read ↗

Molecular strategies to increase yeast iron accumulation and resistance.Semantic proximity Read ↗

Loss of cardiolipin leads to perturbation of mitochondrial and cellular iron homeostasis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.