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Article

Single nucleotide polymorphism and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene in suicide victims.

Biological psychiatry - 15 Oct 2004

Zill Peter, Büttner Andreas, Eisenmenger Wolfgang, Möller Hans-Jürgen, Bondy Brigitta, Ackenheil Manfred

Abstract excerpt

BACKGROUND: Tryptophan hydroxylase, the rate-limiting enzyme in the biosynthesis of serotonin, represents a major candidate in numerous genetic association analyses of suicidal behavior; however, the results are so far inconclusive. Recently, a second tryptophan hydroxylase isoform (TPH2) was identified in mice, which was exclusively present in the brain. In a previous postmortem study of our own group, we could...

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Identifiers

PMID: 15476687
DOI: 10.1016/j.biopsych.2004.07.015

Genes

TPH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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