Article
TPH2 polymorphisms and alcohol-related suicide.
Neuroscience letters - 18 Feb 2011
Zupanc Tomaž, Pregelj Peter, Tomori Martina, Komel Radovan, Paska Alja Videtič
Abstract excerpt
Substantial evidence from family, twin, and adoption studies corroborates implication of genetic and environmental factors, as well as their interactions, on suicidal behavior and alcoholism risk. Serotonergic disfunction seems to be involved in the pathophysiology of substance abuse, and has also an important role in suicidal behavior. Recent studies of the tryptophan hydroxylase 2 showed mild or no association...
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