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Article

TPH2 is not a susceptibility gene for suicide in Japanese population.

Progress in neuro-psychopharmacology & biological psychiatry - 13 Nov 2009

Mouri Kentaro, Hishimoto Akitoyo, Fukutake Masaaki, Shiroiwa Kyoichi, Asano Migiwa, Nagasaki Yasushi, Ueno Yasuhiro, Shirakawa Osamu, Nishiguchi Naoki, Maeda Kiyoshi

Abstract excerpt

BACKGROUND: Serotonergic systems mediate a control of aggression and/or impulsivity in human and are suggested to be involved in suicidal behavior. The newly identified neuronal tryptophan hydroxylase isoform 2 (TPH2), the rate-limiting enzyme in serotonin synthesis, represents a prime candidate in numerous genetic association analyses of suicidal behavior; however, the results are still inconclusive. The...

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Source

Identifiers

PMID: 19748542
DOI: 10.1016/j.pnpbp.2009.09.002

Genes

TPH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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