Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bias in parental transmission of the HLA-DR3 allele in Sardinian multiple sclerosis.

Neurology - 28 Sept 2004

Marrosu M G, Sardu C, Cocco E, Costa G, Murru M R, Mancosu C, Murru R, Lai M, Contu P

Abstract excerpt

The authors analyzed the female: male (F:M) ratio according to the HLA-DRB1-DQB1 genotype in a cohort of multiple sclerosis (MS) patients from Sardinia, where the disease is associated with DR3 and DR4. In the whole cohort of 1,097 patients, F:M ratio was 2.24; however, it was 2.88 in DR3/DR3 and 2.52 in DR3/DRX (X#DR3 and DR4) individuals. Parental transmission of DR3 and DR4, assessed in a set of 565...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Segregation
Share to Fathers
Share to Genes, MHC Class II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-DQ beta-Chains

Share to HLA-DR3 Antigen

Share to HLA-DR4 Antigen

Share to Multiple Sclerosis

Share to Sex Distribution

Source

Identifiers

PMID: 15452304
DOI: 10.1212/01.wnl.0000138493.04890.7c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bias in parental transmission of the HLA-DR3 allele in Sardinian multiple sclerosis.PMID 15452304Read ↗

Multiple Sclerosis in Sardinia Is Associated and in Linkage Disequilibrium with HLA-DR3 and -DR4 AllelesSemantic proximity Read ↗

Sex-related bias and exclusion mapping of the nonrecombinant portion of chromosome Y in human type 1 diabetes in the isolated founder population of Sardinia.Semantic proximity Read ↗

HLA-DRB1-DQB1 haplotypes confer susceptibility and resistance to multiple sclerosis in Sardinia.Semantic proximity Read ↗

HLA-DR,DQ and APOE genotypes and gender influence in Sardinian primary progressive MS.Semantic proximity Read ↗

HLA-DQB1 genotype in Sardinian multiple sclerosis: evidence for a key role of DQB1 *0201 and *0302 alleles.Semantic proximity Read ↗

Parental transmission of HLA-DRB1*15 in multiple sclerosis.Semantic proximity Read ↗

Interaction of loci within the HLA region influences multiple sclerosis course in the Sardinian population.Semantic proximity Read ↗

Parent-of-origin effects at the major histocompatibility complex in multiple sclerosis.Semantic proximity Read ↗

Association between the ancestral haplotype HLA A30B18DR3 and multiple sclerosis in central Sardinia.Semantic proximity Read ↗

Excess of maternal HLA-DR3 antigens in HLA DR3,4 positive type 1 (insulin-dependent) diabetic patients.Semantic proximity Read ↗

Transracial evidence for the influence of the homologous HLA DR-DQ haplotype on transmission of HLA DR4 haplotypes to diabetic children.Semantic proximity Read ↗

The role of HLA-DR alleles and complotypes through the ethnic barrier in systemic lupus erythematosus in Mexicans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.