Article
Interaction of loci within the HLA region influences multiple sclerosis course in the Sardinian population.
Journal of neurology - 1 Feb 2006
Marrosu M G, Cocco E, Costa G, Murru M R, Mancosu C, Murru R, Lai M, Sardu C, Contu P
Abstract excerpt
We examined the influence of alleles at the HLA loci, previously found to be associated with multiple sclerosis (MS) in Sardinia, on the clinical course of the disease in 835 relapsing (R) and 100 primary progressive (PP) patients. Multivariate analysis was carried out on predisposing 0301 or non-associated DPB1 alleles, susceptible or non-associated DRB1-DQB1 haplotypes, both predisposing and non-predisposing,...
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