Article
Association between the ancestral haplotype HLA A30B18DR3 and multiple sclerosis in central Sardinia.
Genetic epidemiology - 1 Feb 2001
Bitti P P, Murgia B S, Ticca A, Ferrai R, Musu L, Piras M L, Puledda E, Campo S, Durando S, Montomoli C, Clayton D G, Mander A P, Bernardinelli L
Abstract excerpt
Association and linkage studies have established the importance of the major histocompatibility complex (MHC) in the susceptibility for multiple sclerosis (MS). We carried out a case-control study to investigate the ancestral haplotype A30B18DR3 and MS in the Nuoro population of Sardinia, which is isolated and genetically distinct from other populations in the Mediterranean basin and characterized by genetic...
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