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Article

HLA-DR,DQ and APOE genotypes and gender influence in Sardinian primary progressive MS.

Neurology - 8 Feb 2005

Cocco E, Sotgiu A, Costa G, Murru M R, Mancosu C, Murru R, Lai M, Contu P, Marrosu M G

Abstract excerpt

The authors examined the influence of APOE and human leukocyte antigen-DRB1-DQB1 polymorphisms on the course of multiple sclerosis in 871 patients, 773 with relapsing and 98 with primary progressive disease, and 348 control subjects. The risk of the primary progressive course was increased (odds ratio = 6.81, p = 0.002) in women carrying the APOE4 but not the DRB1-DQB1 predisposing genotype, suggesting in this...

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Share to Apolipoprotein E4
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Multiple Sclerosis, Chronic Progressive

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Source

Identifiers

PMID: 15699400
DOI: 10.1212/01.WNL.0000150579.54878.00

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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