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Article

Cytotoxic T-lymphocyte antigen 4 gene and recovery from hepatitis B virus infection.

Journal of virology - 1 Oct 2004

Thio Chloe L, Mosbruger Timothy L, Kaslow Richard A, Karp Christopher L, Strathdee Steffanie A, Vlahov David, O'Brien Stephen J, Astemborski Jacquie, Thomas David L

Abstract excerpt

Cytotoxic T-lymphocyte antigen 4 (CTLA-4) is an inhibitory T-cell receptor expressed by activated and regulatory T cells. We hypothesized that single-nucleotide polymorphisms (SNPs) in the gene encoding CTLA-4 may affect the vigor of the T-cell response to hepatitis B virus (HBV) infection, thus influencing viral persistence. To test this hypothesis, we genotyped six CTLA4 SNPs, from which all frequent haplotypes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15452244
DOI: 10.1128/JVI.78.20.11258-11262.2004
PMCID: PMC521829

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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