Article
STAT4 genetic polymorphisms association with spontaneous clearance of hepatitis B virus infection.
Immunologic research - 1 Jun 2015
Lu Yanjun, Zhu Yaowu, Peng Jing, Wang Xiong, Wang Feng, Sun Ziyong
Abstract excerpt
STAT4 signal pathway plays an important role in IFN-γ-mediated antiviral activity. Recent studies show an association of STAT4 polymorphisms with hepatitis B virus (HBV) infection. We therefore investigated the influence of STAT4 polymorphisms on the susceptibility of spontaneous clearance of HBV...
Topics
- Adult
- Alleles
- Case-Control Studies
- Disease Progression
- Female
- Gene Frequency
- Genotype
- Haplotypes
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Linkage Disequilibrium
- Liver Cirrhosis
- Liver Neoplasms
- Male
- Middle Aged
- Odds Ratio
- Polymorphism, Genetic