Article
STAT4 genetic polymorphisms association with spontaneous clearance of hepatitis B virus infection.
Immunologic research - 1 Jun 2015
Lu Yanjun, Zhu Yaowu, Peng Jing, Wang Xiong, Wang Feng, Sun Ziyong
Abstract excerpt
STAT4 signal pathway plays an important role in IFN-γ-mediated antiviral activity. Recent studies show an association of STAT4 polymorphisms with hepatitis B virus (HBV) infection. We therefore investigated the influence of STAT4 polymorphisms on the susceptibility of spontaneous clearance of HBV in a Chinese Han population. Genomic DNA from 288 cases with chronic HBV infection and 288 controls who spontaneously...
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