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Article

Gender-dependent association of CTLA4 polymorphisms with resolution of hepatitis C virus infection.

Journal of hepatology - 1 Mar 2007

Schott Eckart, Witt Heiko, Hinrichsen Holger, Neumann Konrad, Weich Viola, Bergk Alexandra, Halangk Juliane, Müller Tobias, Tinjala Sebastian, Puhl Gero, Neuhaus Peter, Wiedenmann Bertram, Berg Thomas

Abstract excerpt

BACKGROUND/AIMS: A vigorous T-cell response is essential for the resolution of HCV infection. It is modified by co-stimulatory molecules that attenuate T-lymphocyte responses by binding to CTLA4. We investigated whether CTLA4 single nucleotide polymorphisms are associated with the resolution of infection or with the course of disease. METHODS: We enrolled 127 individuals with self-limited and 947 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17150279
DOI: 10.1016/j.jhep.2006.09.011

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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