Article
Relationship between programmed cell death-1 polymorphisms and clearance of hepatitis B virus.
International journal of immunogenetics - 1 Jun 2015
Ülger Y, Bayram S, Sandıkçı M Ü, Akgöllü E, Bekar A
Abstract excerpt
Programmed cell death-1 (PD-1) plays a critical role in regulating T-cell function during hepatitis B virus (HBV) infection. This study investigated the relationship between the polymorphisms of PD-1 gene and the susceptibility to HBV infection. Single nucleotide polymorphisms (SNPs) in PD-1 gene at positions +7146 G>A (guanine to adenine substitution) and +7209 C>T (cytosine to thymine substitution) were...
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