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Article

Comprehensive analysis of class I and class II HLA antigens and chronic hepatitis B virus infection.

Journal of virology - 1 Nov 2003

Thio Chloe L, Thomas David L, Karacki Peter, Gao Xiaojiang, Marti Darlene, Kaslow Richard A, Goedert James J, Hilgartner Margaret, Strathdee Steffanie A, Duggal Priya, O'Brien Stephen J, Astemborski Jacquie, Carrington Mary

Abstract excerpt

Following an acute hepatitis B virus (HBV) infection, clearance or persistence is determined in part by the vigor and breadth of the host immune response. Since the human leukocyte antigen system (HLA) is an integral component of the immune response, we hypothesized that the highly polymorphic HLA genes are key determinants of viral clearance. HLA class I and II genes were molecularly typed in 194 Caucasian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14581545
DOI: 10.1128/jvi.77.22.12083-12087.2003
PMCID: PMC254245

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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